Johns Hopkins University – Anemia

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The purpose of this protocol is to provide treatment with HBOC-201 to patients with
life-threatening anemia for whom allogeneic blood transfusion is not an option. HBOC 201
[hemoglobin glutamer – 250 (bovine)] has been previously studied as an alternative to blood
transfusions in severely anemic patients needing a way to enhance tissue oxygenation.
HBOC-201 is purified, cross-linked and polymerized acellular bovine hemoglobin in a modified
lactated Ringer’s solution, and does not require blood compatibility.

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