Jonsson Comprehensive Cancer Center – Progressive Metastatic Castrate Resistant Prostate Cancer

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The dosage of trametinib for oral administration is 2mg once daily. The patient is instructed
to take the trametinib oncedaily dose at approximately the same time each day, by mouth with
approximately 200 mL (almost 1 cup) of water on an empty stomach, either 1 hour before or 2
hours after a meal.

Rare Disease: