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Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma

Descriptive Information
Brief Title † Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma
Official Title † Präklinische Studie Zur Etablierung Einer Immuntherapie für Das Nebennierenrindenkarzinom - Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma
Brief Summary Adrenocortical carcinoma (ACC) is a rare and heterogeneous malignancy with poor prognosis. Surgical resection of the tumor is the treatment of choice. However, even after complete resection more than 80 % of patients will experience recurrence of disease. Therefore, new treatment options are urgently needed. This pre-clinical study try to lay the foundations for a successful immunotherapy in patients with ACC.
Detailed Description
Study Phase N/A
Study Type † Observational [Patient Registry]
Study Design †
Primary Outcome Measure † To find reasonable antigens for a vaccination therapy in ACC
Secondary Outcome Measure †
Condition † Adrenocortical Carcinoma Cushing's Syndrome
Intervention †
Study Arms / Comparison Groups
Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information
Recruitment Status †
Estimated Enrollment † 70
Start Date † September 2005
Completion Date December 2017
Primary Completion Date December 2011
Eligibility Criteria † Inclusion Criteria: - patients with histological proven adrenocortical carcinoma - healthy persons as control group - Life expectancy > 6 months Exclusion Criteria: - autoimmune diseases - severe clinical condition
Gender All
Ages 18 Years - N/A
Accepts Healthy Volunteers Accepts Healthy Volunteers
Contacts ††
Location Countries † Germany
Administrative Information
NCT ID † NCT00457587
Organization ID Wue-Immuno-ACC-83/05
Secondary IDs ††
Responsible Party Principal Investigator
Study Sponsor † University of Wuerzburg
Collaborators †† Deutsche Krebshilfe e.V., Bonn (Germany)
Investigators † Principal Investigator: Martin Fassnacht, MD, University of Wuerzburg
Information Provided By
Verification Date May 2017
First Received Date † April 4, 2007
Last Updated Date May 7, 2017
† Required WHO trial registration data element.
†† WHO trial registration data element that is required only if it exists.
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