Gait Analysis in MPS IVA

Descriptive Information
Brief Title † Gait Analysis in MPS IVA
Official Title † Gait Analysis in Patients With MPS IVA Treated With Enzyme Replacement Therapy
Brief Summary The purpose of this study is to learn about gait (walking) characteristics in MPS IVA and possible changes in gait with enzyme replacement therapy.
Detailed Description The purpose of this 3-year study is to conduct a longitudinal investigation using motion analysis of gait to objectively and quantitatively assess gait characteristics of MPS IVA patients. Data documenting gait characteristics and abnormalities will be gathered in patients initiating enzyme replacement therapy. Inclusion criteria Individuals with MPS IVA diagnosed by enzyme or molecular studies Exclusion Criteria Individual with MPS IVA previously enrolled in BMN-110 Individual is non-ambulatory The individual is unable to complete longitudinal study visits at least yearly
Study Phase N/A
Study Type † Observational
Study Design † Observational Model: Cohort, Time Perspective: Prospective
Primary Outcome Measure † Measurable changes in gait
Secondary Outcome Measure †
Condition † MPS IVA Morquio Syndrome
Intervention †
Study Arms / Comparison Groups
Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information
Recruitment Status †
Estimated Enrollment † 10
Start Date † August 2013
Completion Date July 2016
Primary Completion Date December 2015
Eligibility Criteria † Inclusion Criteria: -Diagnosis of MPS IVA Exclusion Criteria: Non-ambulatory - Previous enrolled in clinical trial BMN-110
Gender Both
Ages 1 Year - N/A
Accepts Healthy Volunteers No
Contacts ††
Location Countries † United States
Administrative Information
NCT ID † NCT01920828
Organization ID OregonHSU-8833
Secondary IDs ††
Responsible Party Principal Investigator
Study Sponsor † Oregon Health and Science University
Collaborators †† University of Utah
Investigators † : ,
Information Provided By
Verification Date August 2013
First Received Date † August 8, 2013
Last Updated Date August 9, 2013
† Required WHO trial registration data element.
†† WHO trial registration data element that is required only if it exists.
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