Fibrodysplasia ossificans progressiva

Overview

A rare genetic connective tissue disorder characterized by a short toe, fibrous dysplasia and bone formation in muscles, ligaments, tendons and soft connective tissue.

Fibrodysplasia ossificans progressiva is an ultra rare disorder and is believed to occur in approximately 1 in 2 million people worldwide, with only several hundred cases having been reported. 

Symptoms Hide

  • short toe
  • bone fusion in toe
  • short thumb
  • swelling of fibrous tissue
  • pain 
  • fever 
  • swelling in aponeuroses 
  • swelling in fasciae 
  • swelling in tendons
  • progressive fusion of vertebrae
  • scoliosis
  • muscle ossification
  • fibrous tissue ossification
  • restricted arm mobility
  • restricted knee mobility
  • restricted wrist mobility
  • restricted joint movement
  • restricted spine mobility
  • restricted hip mobility
  • restricted shoulder mobility

Causes Hide

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