Jacobs syndrome


A rare chromosomal genetic syndrome where the male person has an extra Y male chromosome, becoming XYY instead of normal XY (male) or XX (female). The person is male and may be mostly normal, or may suffer from minor features from excess male hormones, such as excess acne being very tall, and in some cases behavioral complaints such as aggression.

Symptoms Hide

  • Immaturity
  • Learning difficulties
  • Arthritis
  • Camptodactyly
  • Swollen joints
  • Joint stiffness
  • Impaired joint mobility
  • Inflamed pericardium
  • Chest pain

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