Prader-Willi syndrome


Prader-Willi Syndrome (PWS) is a rare genetic disorder due to an abnormality on the 15th chromosome resulting in an excessive preoccupation with food and constant hunger, which in turn can lead to obesity and obesity–related health problems.

source: Prader-Willi

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Symptoms may include:

• Almond-shaped eyes

• Delayed motor development

• Floppy newborn infant

• Insatiable appetite, food craving

• Irregular areas of skin that look like bands, stripes, or lines

• Narrow bifrontal skull

• Rapid weight gain

• Skeletal (limb) abnormalities

• Slow mental development

• Small for gestational age

• Undescended testicles in the male infant

• Very small hands and feet in comparison to body

Affected children have an intense craving for food and will do almost anything to get it. This results in uncontrollable weight gain and morbid obesity. Morbid obesity may lead to lung failure with low blood oxygen levels, right-sided heart failure, and death.

source: PWS

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