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Abdominal obesity metabolic syndrome

Metabolic syndrome X, AOMS1

Overview

Abdominal obesity metabolic syndrome is a syndrome characterized by a group of conditions that are considered major risk factors for diabetes mellitus and cardiovascular disease.

Symptoms - Abdominal obesity metabolic syndrome

The list of signs and symptoms mentioned in various sources for Abdominal obesity metabolic syndrome includes 

  • High body mass index
  • Excessive waist circumference
  • Abdominal obesity
  • High waist/hip ratio
  • High blood pressure
  • High triglyceride level
  • Low HDL cholesterol level
  • High prothrombin level
  • Microalbuminuria
  • Abnormal fasting glucose
  • Impaired glucose tolerance
  • Insulin resistance

Causes - Abdominal obesity metabolic syndrome

  • Exogenous obesity (most common) –No demonstrable disease as the cause –Excessive weight gain from imbalance between caloric intake and energy expenditure –Linear growth is robust and frequently accelerated
  • Hormonal causes –Associated with poor linear growth –Hypercortisolism: Cushing syndrome is any type of glucocorticoid excess (endogenous or exogenous); Cushing disease describes pituitary ACTH overproduction –Hypothyroidism –Growth hormone deficiency
  • Insulinoma
  • Hypothalamic obesity –Tumors (e.g., craniopharyngiomas) –Following neurosurgery or irradiation –Head trauma –Infiltrative/inflammatory
  • Genetic syndromes –Prader-Willi syndrome –Laurence-Moon-Bardet-Biedl syndrome –Alström syndrome –Cohen syndrome –Down syndrome –Carpenter syndrome –Grebe syndrome –Beckwith-Wiedemann syndrome o Defects in metabolic/eating regulatory pathways is an area of intense investigation; multiple mutations are theoretically possible, but only a few have actually been discovered in humans –Congenital leptin deficiency (extremely rare) –Leptin resistance (more common than deficiency)
  • Drugs –Chronic glucocorticoids –Neuropsychotropic medications o Adiposogenital dystrophy syndrome

Prevention - Abdominal obesity metabolic syndrome

Not supplied.

Diagnosis - Abdominal obesity metabolic syndrome

These home medical tests may be relevant to Abdominal obesity metabolic syndrome:

  • High Cholesterol: Home Testing; Home Cholesterol Tests; Home Triglycerides Tests; Home Blood Pressure Tests
  • High Blood Pressure;Home Testing o Home Blood Pressure Monitors o Home Heart Tests
  • Heart Health: Home Testing: o Heart Rate Monitors o Irregular Heartbeat Detection o Heart Electrocardiogram (ECG)
  • Thyroid: Home Testing: o Home Thyroid Function Tests o Home TSH Tests o Home Adrenal Function Tests
  • Diet & Weight Loss: Home Testing: o Home Weight Testing o Home Body Fat Testing (BMI) o Home Body Fat Monitoring o Home Fitness Testing
  • Diabetes: Related Home Testing: o Home Diabetes Tests o Home Blood Glucose Tests o Home Urine Glucose Tests o Home Urine Ketone Tests o Home Diabetes HbA1c Tests o Home Microalbumin Tests (Kidney) o Home Urine Protein Tests (Kidney) o Home Kidney Tests o Home Eye Tests

Prognosis - Abdominal obesity metabolic syndrome

Not supplied.

Treatment - Abdominal obesity metabolic syndrome

  • If syndrome or no known disease as etiology –Nutritional education and diet manipulation –Exercise regimen (energy expenditure must exceed intake) –Behavior modification involving family
  • Hormonal etiology –Hormone replacement for hypothyroidism or growth hormone deficiency –Surgical intervention if hypercortisolism caused by tumor –Decrease exogeneous glucorticoids if not medically contraindicated

* Leptin treatment in leptin deficiency (therapeutic trials)

* If patient also has type II diabetes mellitus, insulin or oral medications may be required in addition to improved diet and exercise

Resources - Abdominal obesity metabolic syndrome

  • NIH
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