Biliary atresia- extrahepatic
Overview
EHBA is a progressive congenital disorder that destroys the external bile duct structure of the liver, impairing normal bile flow (cholestasis). The condition affects one in 10,000 to 20,000 newborns and is the most frequent liver surgical disorder in infants. More common in females, its cause is unknown. Infants with EHBA typically appear healthy at birth, with normal development and weight gain. As EHBA grows worse, growth may be retarded.
Symptoms
EHBA
Causes
No cause for the lesion was found in infants with extrahepatic biliary atresia, but in 32 with hepatitis a specific cause was identified, 24 having genetic deficiency of the serum protein alpha1-antitrypsin.