Buschke Lowenstein Tumor
Overview
Buschke Lowenstein Tumor (medical condition): A low grade wart-like tumor believed to be caused by HPV (human papilloma virus) infections. The tumor is occurs in the genital area and there is still some contention about whether the tumor is benign or borderline cancerous.
Symptoms
The list of signs and symptoms mentioned in various sources for Buschke-Lowenstein Tumor includes the 1 symptoms listed below: * Genital wart-like lump Note that Buschke-Lowenstein Tumor symptoms usually refers to various symptoms known to a patient, but the phrase Buschke-Lowenstein Tumor signs may refer to those signs only noticable by a doctor.
Causes
Chronic phimosis and poor penile hygiene have been postulated as inciting or contributing events. This may account for the higher incidence in males who are uncircumcised. Populations with a higher incidence of circumcision have a lower rate of GCBL. In general, newborn circumcision has been estimated to be 99.9% effective in eliminating cancer of the penis. Chronic irritation, produced by a perianal fistula and ulcerative colitis, has been implicated as a causative factor. Immunosuppression secondary to HIV disease or due to immunosuppressive medication may be a predisposing factor. Other risk factors for GCBL are low socioeconomic status, drug abuse, use of oral contraceptives, presence of other sexually transmitted diseases, diabetes, smoking, and, possibly, pregnancy,4 which may be associated with an impaired immune response.