Close
Close

GAPO syndrome

Overview

GAPO syndrome is a rare genetic disorder. GAPO is an acronym for growth retardation, alopecia, pseudoanodontia (failure of tooth eruption), and progressive optic atrophy.

Symptoms - GAPO syndrome

* Reduced birth length * Growth retardation * Absence of scalp hair * Non-erupting teeth * Protruding forehead

Causes - GAPO syndrome

* Papilledema: Lasts seconds, bilateral * Amaurosis fugax: Lasts minutes, unilateral * Vertebrobasilar artery insufficiency: Lasts minutes, bilateral * Migraine: Lasts 10–60 minutes * Impending central retinal vein occlusion * Ocular ischemic syndrome (carotid occlusive disease) * Sudden change in blood pressure; orthostatic hypotension * Transient acute increase in intraocular pressure (e.g., acute angle closure glaucoma, retro- or peribulbar hemorrhage)

Prevention - GAPO syndrome

Not supplied.

Diagnosis - GAPO syndrome

Not supplied.

Prognosis - GAPO syndrome

Not supplied.

Treatment - GAPO syndrome

Treat underlying causes (e.g., brain tumor, carotid stenosis, cardiac valvular vegetations, hypotension) Temporal arteritis: Systemic steroids Nonarteritic ischemic optic neuropathy: Aspirin Optic neuritis: Systemic steroids Glaucoma: Topical antiglaucoma medications; peripheral iridotomy for angle closure Retinal detachment: Surgical repair Cataracts: Surgical removal AV fistula: Embolize Cavernous sinus thrombosis: Antibiotics, anticoagulation Mucormycosis: Amphotericin B, debridement Pituitary apoplexy: Systemic steroids, neurosurgical intervention Herpes zoster: Systemic acyclovir Tolosa-Hunt: Systemic steroid

Resources - GAPO syndrome

Not supplied.
Videos
Currently no videos.
To submit one, CLICK HERE
Clinical Trials
No clinical trial found
Research Publications