Henoch-Schonlein purpura

Overview

Alternative Names: Anaphylactoid purpura; Vascular purpura. Henoch-Schonlein purpura is a disease that involves purple spots on the skin, joint pain, gastrointestinal problems, and glomerulonephritis (a type of kidney disorder).

Symptoms

  •  Abdominal pain 
  • Bloody stools 
  • Hives or angioedema 
  • Joint pain 
  • Nausea 
  • Diarrhea 
  • Painful menstruation 
  • Purple spots on the skin (purpura), usually over the buttocks, lower legs, and elbows 
  • Vomiting

Causes

Henoch-Schonlein is a type of hypersensitivity vasculitis and inflammatory response within the blood vessel. It is caused by an abnormal response of the immune system. It is unclear why this occurs. The syndrome is usually seen in children, but it may affect people of any age. It is more common in boys than in girls. Many people with Henoch-Schonlein purpura had an upper respiratory illness in the previous weeks.

Diagnosis

The doctor will examine your body and look at your skin. The physical exam will reveal skin lesions and joint tenderness. A urinalysis shows microscopic blood in the urine. A skin biopsy shows vasculitis.

Prognosis

The disease usually resolves spontaneously without treatment.

Resources

Call for an appointment with your health care provider if: 

  • Symptoms of Henoch-Scholnlein purpura develop, particularly if they last for more than a few days 
  • If low urine output develops after an episode of Henoch-Schonlein purpura