Navajo poikiloderma

Overview

A rare genetic blood disorder found in Navajo populations and characterized by a progressive skin disorder and neutropenia (lack of neutrophils which are needed to fight bacterial infections). Navajo poikiloderma is listed as a ""rare disease"" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Navajo poikiloderma, or a subtype of Navajo poikiloderma, affects less than 200,000 people in the US population. "

Symptoms

Neutropenia Poikiloderma Spreading skin rash Recurring respiratory infections Recurring sinus infection Abnormal skin pigmentation Thick nails Nail infection

Diagnosis

The phrase "signs of Navajo poikiloderma" should, strictly speaking, refer only to those signs and symptoms of Navajo poikiloderma that are not readily apparent to the patient. The word "symptoms of Navajo poikiloderma" is the more general meaning; see symptoms of Navajo poikiloderma. The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Navajo poikiloderma. This medical information about signs and symptoms for Navajo poikiloderma has been gathered from various sources, may not be fully accurate, and may not be the full list of Navajo poikiloderma signs or Navajo poikiloderma symptoms. Furthermore, signs and symptoms of Navajo poikiloderma may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Navajo poikiloderma symptoms.