Spastic paraplegia with Kallmann syndrome

December 31, 2014

Overview

Spastic paraplegia with Kallmann syndrome: A very rare genetic disorder characterized mainly by mild spasticity and weakness of the lower legs as well as lack of sex hormone production and an inability to smell.

Symptoms

Lower leg weakness Lower leg spasticity Hypogonadism Inability to smell Delayed puberty

Causes

Conditions listing Spastic paraplegia with Kallmann syndrome as a symptom may also be potential underlying causes of Spastic paraplegia with Kallmann syndrome. Our database lists the following as having Spastic paraplegia with Kallmann syndrome as a symptom of that condition: Choreoathetosis-spasticity, episodic Chromosome 8p inverted duplication syndrome Leukoencephalopathy - metaphyseal chondrodysplasia Macrocephaly, mental retardation, short stature, spastic paraplegia and CNS malformations Mental retardation, X-linked, syndromic, due to JARID1C mutation Oculocerebral syndrome with hypopigmentation Roy-Maroteaux-Kremp syndrome Spastic paraplegia 30, autosomal recessive Spastic paraplegia 31, autosomal dominant Spastic paraplegia 32, autosomal recessive Spastic paraplegia 33, autosomal dominant Spastic paraplegia 4, autosomal dominant Spastic paraplegia 7, autosomal recessive