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Researchers Funded by the Pancreatic Cancer Action Network Leverage $9.15 Million Investment by the Organization Into $91 Million in Subsequent Pancreatic Cancer Research Funding
Thursday, May 16, 2013
A rigorous analysis of the Pancreatic Cancer Action Network research grants program has shown that the organization's grant recipients are leveraging their awards to secure impressive subsequent funding, publishing their findings, and enhancing knowledge about the disease. The organization Upon fu
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PARP Inhibitor Shows Activity in Pancreatic, Prostate Cancers Among Patients Carrying BRCA Mutations
Thursday, May 16, 2013
In the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers. Results of the study, led by The multi
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Proteome Atlas for the Tuberculosis Pathogen
Thursday, May 16, 2013
Photographers know the problem all too well: with the naked eye, you can see which branch a bird is sitting on, but spotting the bird in the blur of branches through the telephoto lens for high-magnification images requires considerable skill. It is a similar story for researchers who are looking
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No Idle Chatter: Study Finds Malaria Parasites 'Talk' to Each Other
Thursday, May 16, 2013
Melbourne scientists have made the surprise discovery that malaria parasites can 'talk' to each other – a social behaviour to ensure the parasite's survival and improve its chances of being transmitted to other humansThe finding could provide a niche for developing antimalarial drugs and vaccine
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Hot on the TRAIL of Graft vs. Host Disease
Thursday, May 16, 2013
For patients with leukemia and other hematological malignancies, transplantation ofhematopoietic stem cells (HSCT) can be a powerfully effective therapy. In addition to thedesirable anti-tumor effect, transplanted cells can also attack the host tissue, resulting in graftversus-host disease (GVHD
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New Drug Enhances Radiation Treatment for Brain Cancer in Preclinical Studies
Thursday, May 16, 2013
A novel drug may help increase the effectiveness of radiation therapy for the most deadly form of brain cancer, report scientists at Virginia Commonwealth University Massey Cancer Center. In mouse models of human glioblastoma multiforme (GBM), the new drug helped significantly extend survival when
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Pitt Transplant Experts Challenge Assumption, Describe Pathway That Leads to Organ Rejection
Thursday, May 16, 2013
Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation. Their study, sponsored by the National
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Widespread but Neglected Disease a Health Threat in Africa, Virginia Tech Researchers Say
Wednesday, May 15, 2013
The newest public health threat in developing countries may not be a cinematic-quality emerging disease but actually a disease from animals that was identified more than 100 years agoVirginia Tech researchers have identified leptospirosis as a significant health threat in Botswana. The world's mos
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Leap in Leukemia Treatment Reported by Dartmouth Researchers
Tuesday, May 14, 2013
Doctors at Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) have found a combination of drugs to potentially treat chronic lymphocytic leukemia (CLL) more effectively. The research was published online on May 3, 2013, and it will appear as a letter in the journal Leukemia, a publication of
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Breakthrough in the Understanding of How Pancreatic Cancer Cells Ingest Nutrients Points to New Drug Target
Tuesday, May 14, 2013
In a landmark cancer study published online in Nature, researchers at NYU School of Medicine have unraveled a longstanding mystery about how pancreatic tumor cells feed themselves, opening up new therapeutic possibilities for a notoriously lethal disease with few treatment options. Pancreatic Now