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    New Discovery Could Uncover 'Missing Link' in Genetics

    Friday, February 14, 2014

    Researchers believe that susceptibility to common diseases stems from a combination of common genetic variants and a variety of rare genetic mutations. But this only accounts for a small proportion of potential heritable risk factors for disease. Now, new research has discovered that some genetic

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    TGen and Mayo Clinic Researchers Use Genomic Sequencing to Help Identify New Therapies for Bile Duct Cancer

    Friday, February 14, 2014

    SCOTTSDALE, Ariz.,  Researchers at the Translational Genomics Research Institute (TGen) and physicians at Mayo Clinic’s Individualized Medicine Clinic have personalized drug treatments for patients with cholangiocarcinoma using genomic sequencing technologiesPotential new treatment approaches a

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    A Promising New Approach for Treating Leukemia Discovered

    Thursday, February 13, 2014

    A group of researchers at the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That gene, known as Brg1 is a key regulator of leukemia stem cells

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    Laboratory Detective Work Points to Potential Therapy for Rare, Drug-resistant Cancer

    Thursday, February 13, 2014

    PITTSBURGH,  – University of Pittsburgh Cancer Institute (UPCI) scientists have shown that old drugs might be able to do new tricksBy screening a library of FDA-approved anticancer drugs that previously wouldn't have been considered as a treatment for a rare type of cancer, UPCI scientists were

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    Exon Skipping Prevents Formation of Toxic Protein Fragments in Huntington's Disease

    Wednesday, February 12, 2014

    New Rochelle, NY, — An innovative therapeutic strategy for reducing the levels of toxic protein fragments associated with Huntington's disease uses a new approach called exon skipping to remove the disease-causing component of the essential protein, huntingtin. Proof of concept using antisense

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    Breast Cancer Drug Fights Fungal Disease

    Tuesday, February 11, 2014

    Tamoxifen, a drug currently used to treat breast cancer, also kills a fungus that causes a deadly brain infection in immunocompromised patients. The findings, which could lead to new treatments for a disease that kills more HIV/AIDS patients than tuberculosis, appear in mBio®, the online open-"T

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    New DNA Editing Discovery Could Lead to Cure of Cystic Fibrosis, Sickle Cell Anaemia & Other Genetic Diseases

    Tuesday, February 11, 2014

    Researchers at the Gladstone Institute of Cardiovascular Disease, San Francisco, California, have developed an innovative technique that can efficiently edit the human genetic code — one letter at a time, and which eventually could boost scientists’ ability to study — and ultimately cure —

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    ‘Cut-and-paste’ Gene Defect Hints at Cause of Developmental Disease

    Tuesday, February 11, 2014

    Melbourne researchers have made a major step forward in understanding how changes in an essential cellular process, called minor class splicing, may cause a severe developmental diseaseUsing zebrafish, which is a popular laboratory model for studying development, the researchers discovered tha

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    Clues to Cancer Pathogenesis Found in Cell-conditioned Media

    Monday, February 10, 2014

    Philadelphia, PA,  – Primary effusion lymphoma (PEL) is a rare B-cell neoplasm distinguished by its tendency to spread along the thin serous membranes that line body cavities without infiltrating or destroying nearby tissue. By growing PEL cells in culture and analyzing the secretome (proteins

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    Cochlear Implants -- With No Exterior Hardware

    Monday, February 10, 2014

    Cochlear implants — medical devices that electrically stimulate the auditory nerve — have granted at least limited hearing to hundreds of thousands of people worldwide who otherwise would be totally deaf. Existing versions of the device, however, require that a disk-shaped transmitter about an

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