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    Pharmacyclics Announces Presentation of Phase III and Long Term Follow Up Data on IMBRUVICA™ In Chronic Lymphocytic Leukemia (CLL) at ASCO

    Wednesday, April 23, 2014

    Pharmacyclics, Inc. announced that data from the Phase III PCYC-1112 (RESONATE™) study of single agent IMBRUVICA™ (ibrutinib) vs. ofatumumab, an established therapy in relapsed refractory CLL, as well as data from an Independent Efficacy Evaluation of IMBRUVICA after three years of follow-up, will be presented at the American Society of Clinical Oncology (ASCO) 50th Annual Meeting in Chicago …

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    Repeats in Human DNA May Aggravate Autism Symptoms

    Wednesday, April 23, 2014

    Certain DNA repeats that increased exponentially during human evolution are directly related to the severity of autism symptoms, according to a preliminary study published 20 March in PLoS Genetics 1The repeats each span 65 amino acids and are collectively referred to as DUF1220, for ‘domain of unknown function.’ There are six types of these repeats, each with a slightly different sequence a …

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    European Commission Grants Orphan Drug Designation to Soliris® (Eculizumab) for the Prevention of Graft Rejection Following Solid Organ Transplantation

    Wednesday, April 23, 2014

    Alexion Pharmaceuticals, Inc. today announced that the European Commission has granted an orphan drug designation (ODD) to Soliris® (eculizumab), a first-in-class terminal complement inhibitor, for the prevention of graft rejection following solid organ transplantation. Graft rejection can cause severe injury to the transplanted organ and is a significant barrier to successful transplantation.

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    Girl Trapped in an Indoors Bubble Saved by Sister's Bone Marrow Transplant

    Tuesday, April 22, 2014

    Six-year-old Milly Smith was born with a disease suffered by one in eight million girls which left her with no immune system, meaning just going outdoors could be fatalThen a routine test to check that eight-year-old sister Kacey did not have the same condition revealed she was a perfect bone marrow match for Milly.

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    Lupus Sufferer Holding Photo Competition to Raise Awareness of Rare Illness

    Tuesday, April 22, 2014

    A photographer is to hold a picture competition to raise awareness of a rare illnessJess Tilston, 22, is the owner of Just Picture It, a photography studio located in Abbeygate, GrimsbyShe suffers from the auto immune disease Lupus, which is a serious, life-altering illness that can affect any or

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    Children's Tumor Foundation Extends Successful Art Car Program

    Tuesday, April 22, 2014

    The Children’s Tumor Foundation (CTF) Racing4Research (R4R) program will extend its highly successful "Art Car" effort with a full-season in the Pirelli World Challenge. Building on momentum begun at Daytona and Sebring earlier this year, the charity has partnered with Compass360 Racing (C360R), which fields cars in both GTS and TC classes.The cars will feature livery inspired by a signature …

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    Two Genes Linked to Inflammatory Bowel Disease

    Tuesday, April 22, 2014

    Inflammatory Bowel Disease (IBD), a group of chronic inflammatory disorders of the intestine that result in painful and debilitating complications, affects over 1.4 million people in the U.S., and while there are treatments to reduce inflammation for patients, there is no cureNow, Cincinnati Cancer Center and University of Cincinnati Cancer Institute researcher Susan Waltz, PhD, and scientists in …

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    Salk Lab Turns Skin Cells Into Human Airway Tissue

    Tuesday, April 22, 2014

    Using reprogrammed skin cells, researchers have for the first time used stem cell techniques to grow fully functional assemblies of the cells that line airways leading to the lungs. The lab-grown airway tissue can now be used to study the molecular basis for lung diseases—from rare genetic disorders to common afflictions like asthma and emphysema—and test new drugs to treat the diseases.

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    Rising Awareness: This 3rd of May Unite Against Scleroderma 2014

    Tuesday, April 22, 2014

    For the fourth year running, the Scleroderma Care Foundation will be hosting their annual Unite Against Scleroderma Awareness Walk. Scheduled to start from 2:30pm, the Walk would be held on Saturday 3rd May, 2014 and cover one full lap around the Queen’s Park Savannah, Port of Spain. They have

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    Diagnosed at Last: Phevor Software IDs Disease-Causing Gene Mutations in 3 Children

    Tuesday, April 22, 2014

    A computational tool developed at the University of Utah (U of U) has successfully identified diseases with unknown gene mutations in three separate cases, U of U researchers and their colleagues report in a new study in The American Journal of Human Genetics. The software, Phevor (Phenotype Driven

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