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Chronic granulomatous disease

Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus.
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Aspergillus nodules in chronic granulomatous disease attributable to Aspergillus ochraceus.

Med Mycol Case Rep. 2017 Sep;17:31-33

Authors: Moazam S, Denning DW

Abstract
Aspergillus ochraceus is a rare pulmonary pathogen. A 39 year old male with COPD and chronic granulomatous disease presented with severe breathlessness and recurrent infections. CT scan demonstrated multiple pulmonary nodules diagnosed as chronic pulmonary aspergillosis. The patient's sputum grew Aspergillus ochraceus thrice over 6 months, alongside positive Aspergillus IgG and serum galactomannan. Despite treatment with itraconazole, the patient continued to be symptomatic. We present the first case associating A. ochraceus with chronic pulmonary aspergillosis.

PMID: 28702318 [PubMed]

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