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Chronic granulomatous disease

Investigation of bovine tuberculosis outbreaks using the trace-back system and molecular typing in Korean Hanwoo beef cattle.
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Investigation of bovine tuberculosis outbreaks using the trace-back system and molecular typing in Korean Hanwoo beef cattle.

J Vet Sci. 2017 Jul 10;

Authors: Ku BK, Jeon BY, Kim JM, Jang YB, Lee H, Choi JY, Jung SC, Nam HM, Park H, Cho SN

Abstract
Bovine tuberculosis is a chronic contagious disease responsible for major agricultural economic losses. Abattoir monitoring and trace-back systems are an appropriate method to control bovine tuberculosis, particularly in beef cattle. In the present study, a trace-back system was applied to bovine tuberculosis outbreaks of Korean native Hanwoo beef cattle. Bovine tuberculosis was detected in three index beef cattle during abattoir monitoring in Jeonbuk Province, Korea, and the original herds were traced back from each index cattle. All cattle in the original herds were subjected to tuberculin skin test. The positive rates of the tuberculin skin test were 64.2% (62 of 96), 2.4% (2 of 42) and 8.1% (3 of 37) at farms A, B and C, respectively. In the post-mortem examination of 56 tuberculin-positive cattle, 62% had granulomatous lesions, and Mycobacterium bovis was cultured from 40 (71.4%) cattle. Molecular typing by spoligotyping and the mycobacterial interspersed repetitive unit-variable number tandem repeat assay revealed the genotype of the M. bovis strains from the index cattle were same as the M. bovis genotype in each original herd. These results suggest that tracing back from the index cattle to the original herd is an effective method to control bovine tuberculosis in beef cattle.

PMID: 28693300 [PubMed - as supplied by publisher]