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Soft tissue sarcomas

Surgical treatment associated with improved survival in patients with cutaneous angiosarcoma.

Surgical treatment associated with improved survival in patients with cutaneous angiosarcoma.

J Eur Acad Dermatol Venereol. 2017 Jul 14;:

Authors: Trofymenko O, Curiel-Lewandrowski C

Abstract
Cutaneous angiosarcoma is a rare aggressive vasoformative neoplasm of the skin with a poor prognosis.(1) The neoplasm preferentially involves areas of head and neck and usually diagnosed in advanced stage.(1, 2) The neoplasm accounts for only 2% of soft-tissue sarcomas in the U.S. and most often affects elderly white males, patients treated with radiation, and individuals with certain chronic lymphatic disorders.(3) Surgery with or without adjuvant or neoadjuvant radiation therapy (RT) is considered the mainstay of therapy.(1, 3) Due to low incidence rates, the clinical outcomes data has been limited to case reports and single institution studies, with a lack of direct comparison between various treatment modalities: surgery, RT, and chemotherapy (CT).(4, 5) In this study, we aimed to investigate the impact of undergoing different therapeutic approaches on long-term overall survival (OS) using cross-institutional data. This article is protected by copyright. All rights reserved.

PMID: 28710797 [PubMed - as supplied by publisher]

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