Close
Close

Beta-thalassemia

Clinical Classification, Screening and Diagnosis for Thalassemia.
Related Articles

Clinical Classification, Screening and Diagnosis for Thalassemia.

Hematol Oncol Clin North Am. 2018 Apr;32(2):193-211

Authors: Viprakasit V, Ekwattanakit S

Abstract
At present, thalassemia diseases are classified into transfusion-dependent thalassemia and non-transfusion-dependent thalassemia. This classification is based on the clinical severity of patients determining whether they do require regular blood transfusions to survive (transfusion-dependent thalassemia) or not (non-transfusion-dependent thalassemia). In addition to the previous terminology of "thalassemia major" or "thalassemia intermedia," this classification has embraced all other forms of thalassemia syndromes such as α-thalassemia, hemoglobin E/β-thalassemia and combined α- and β-thalassemias. Definitive diagnosis of thalassemia and hemoglobinopathies requires a comprehensive workup from complete blood count, hemoglobin analysis, and molecular studies to identify mutations of globin genes.

PMID: 29458726 [PubMed - in process]

Videos
by Abidemi Uruejoma
12 views
by Abidemi Uruejoma
31 views
by Abidemi Uruejoma
49 views