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Treatment Database

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Product Indication Date Designated
Polymeric oxygen Sickle cell anemia Mar 25, 1992
Melphalan For use in hyperthermic regional limb perfusion to treat metastatic melanoma of the extremity Mar 03, 1992
Pilocarpine HCl Xerostomia and keratoconjunctivitis sicca in Sjogren's syndrome patients Feb 28, 1992
Melphalan Patients with multiple myeloma for whom oral therapy is inappropriate Feb 24, 1992
Loxoribine Common variable immunodeficiency Feb 24, 1992
Ciliary neurotrophic factor Amyotrophic lateral sclerosis Jan 30, 1992
Cystic fibrosis transmembrane conductance regulator For cystic fibrosis transmembrane conductance regulator protein replacement therapy in cystic fibrosis patients Jan 14, 1992
Cryptosporidium hyperimmune bovine colostrum IgG concentrate Diarrhea in AIDS patients caused by infection with Cryptosporidium parvum Dec 30, 1991
botulinum toxin type A Dynamic muscle contracture in pediatric cerebral palsy patients Dec 06, 1991
Monoclonal antibody to cytomegalovirus (human) Cytomegalovirus retinitis in patients with AIDS Nov 15, 1991
Halofantrine Mild to moderate acute malaria caused by susceptible strains of P. falciparum and P. vivax. Nov 04, 1991
Synthetic derivative of 16-hydroxy-9Z, 12Z, 14E-octadecatrienoic acid Prophylactic treatment of sickle cell disease Oct 24, 1991
Lodoxamide tromethamine Vernal keratoconjunctivitis Oct 16, 1991
Dynamine Hereditary motor and sensory neuropathy type I (Charcot-Marie-Tooth disease) Oct 16, 1991
Monoclonal antibody to cytomegalovirus (human) Prophylaxis of cytomegalovirus disease in patients undergoing solid organ transplantation Sep 13, 1991
Filgrastim Patients with AIDS who, in addition, are afflicted with cytomegalovirus retinitis and are being treated with ganciclovir Sep 03, 1991
Mecasermin Amyotrophic lateral sclerosis Aug 05, 1991
mecasermin Amyotrophic lateral sclerosis Aug 05, 1991
Ursodiol Patients with primary biliary cirrhosis Jun 20, 1991
Alpha-galactosidase A Alpha-galactosidase A deficiency (Fabry's disease) Jun 17, 1991