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Treatment Database

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Product Indication Date Designated
Amifostine For use as a chemoprotective agent for cisplatin in the treatment of metastatic melanoma May 30, 1990
Amifostine For use as a chemoprotective agent for cyclophosphamide in the treatment of advanced ovarian carcinoma May 30, 1990
Amifostine For use as a chemoprotective agent for cisplatin in the treatment of advanced ovarian carcinoma May 30, 1990
Short chain fatty acid solution The active phase of ulcerative colitis with involvement restricted to the left side of the colon May 29, 1990
PR-225 (redox-acyclovir) Herpes simplex encephalitis in individuals afflicted with AIDS May 29, 1990
Interferon alfa-2a (recombinant) For the treatment of metastatic malignant melanoma in combination with Teceleukin May 11, 1990
Granulocyte macrophage-colony stimulating factor Chronic lymphocytic leukemia to increase granulocyte count May 04, 1990
Anti-cytomegalovirus monoclonal antibodies 1. human cytomegalovirus infection in patients diagnosed with AIDS 2. Prevention of human cytomegalovirus infection in patients diagnosed with AIDS May 03, 1990
Anti-cytomegalovirus monoclonal antibodies 1. human cytomegalovirus infection in bone marrow and organ transplant patients 2. Prevention of human cytomegalovirus infection in bone marrow and organ transplant patients May 02, 1990
chelmab-y or chelamusab-Y Ovarian cancer Apr 24, 1990
Thalidomide Graft versus host disease Mar 05, 1990
Thalidomide Prevention of graft versus host disease Mar 05, 1990
Dynamine Lambert Eaton myasthenic syndrome Feb 05, 1990
polifeprosan 20 with carmustine Malignant glioma Dec 13, 1989
polifeprosan 20 with carmustine Malignant glioma Dec 13, 1989
4-aminosalicylic acid Mild to moderate ulcerative colitis in patients intolerant to sulfasalazine Dec 13, 1989
Perfosfamide For use in the ex-vivo treatment of autologous bone marrow and subsequent reinfusion in patients with acute myelogenous leukemia, also referred to as acute nonlymphocytic leukemia Dec 04, 1989
Porfimer sodium For the photodynamic therapy of patients with transitional cell carcinoma in situ of the urinary bladder Nov 15, 1989
Pegaspargase Acute lymphocytic leukemia Oct 20, 1989
Colfosceril palmitate, cetyl alcohol, tyloxapol 1. Prevention of hyaline membrane disease, also known as respiratory distress syndrome, in infants born at 32 weeks gestation or less 2. prevention of hyaline membrane disease (HMD), also known as respiratory distress syndrome (RDS), in infants born at 32 weeks gestation or less and in the treatment of established HMO at all gestational ages. Oct 20, 1989