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Treatment Database

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Product Indication Date Designated
cladribine Chronic lymphocytic leukemia Dec 31, 1990
3,4-diaminopyridine Lambert-Eaton myasthenic syndrome Dec 18, 1990
Amifampridine Lambert-Eaton myasthenic syndrome Dec 18, 1990
amifampridine Lambert-Eaton myasthenic syndrome Dec 18, 1990
Cladribine Hairy cell leukemia Nov 15, 1990
Mucoid exopolysaccharide Pseudomonas hyperimmune globulin Prevention of pulmonary infections due to Pseudomonas aeruginosa in patients with cystic fibrosis Nov 07, 1990
Filgrastim Patients with severe chronic neutropenia (absolute neutrophil count less than 500/mm3) Nov 07, 1990
Succimer Prevention of cystine kidney stone formation in patients with homozygous cystinuria who are prone to stone development Nov 05, 1990
Calcitonin salmon nasal spray Symptomatic Paget's disease (osteitis deformans) Oct 29, 1990
Tretinoin Acute promyelocytic leukemia Oct 24, 1990
Gossypol Cancer of the adrenal cortex Oct 22, 1990
Taxol isolated from Taxus brevifolia Ovarian cancer Oct 15, 1990
Hydroxyurea Patients with sickle cell anemia as shown by the presence of hemoglobin S Oct 01, 1990
Triptorelin pamoate For use in the palliative treatment of advanced ovarian carcinoma of epithelial origin Aug 10, 1990
Liothyronine sodium injection Myxedema coma/precoma Jul 30, 1990
Alpha-galactosidase A Fabry's disease Jul 20, 1990
Amiloride HCl solution for inhalation Cystic fibrosis Jul 18, 1990
L-baclofen Trigeminal neuralgia Jul 13, 1990
Coagulation Factor IX (human) For use as replacement therapy in patients with hemophilia B for the prevention and control of bleeding episodes, and during surgery to correct defective hemostasis Jul 05, 1990
Calcium carbonate Hyperphosphatemia in patients with end stage renal disease Jun 06, 1990