Treatment Database

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Product Indication Date Designated
1-{3-fluoro-4-[7-(5-methyl-lH-imidazol-2-yl)- 1-oxo-2,3-dihydro-lH-isoindo 1-4-yl]-phenyl}-3-(3-trifluoromethyl-phenyl)-urea Acute myeloid leukemia (AML) Dec 22, 2017
2-O, 3-O, desulfated heparin Acute myeloid leukemia Dec 21, 2017
THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer Acute myeloid leukemia Oct 24, 2017
6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one monocitrate Acute myeloid leukemia (AML) Oct 03, 2017
1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy) phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide fumarate salt Acute Myeloid Leukemia Sep 28, 2017
ICG136:CD123-CD33cCAR T-cells Acute myeloid leukemia Sep 19, 2017
tetravalent tandem diabody binding both CD3 and CD33 Patients with acute myeloid leukemia (AML) Aug 17, 2017
tamibarotene Acute myeloid leukemia (AML) Aug 16, 2017
Gilteritinib Acute myeloid leukemia (AML) Jul 13, 2017
Glasdegib Acute myeloid leukemia (AML) Jun 28, 2017
chrysoeriol Acute myeloid leukemia Jun 22, 2017
(2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl]oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate Acute myeloid leukemia (AML) Jun 21, 2017
entospletinib Acute myeloid leukemia Jun 15, 2017
Sodium Stibogluconate Acute myeloid leukemia Jun 05, 2017
mutated isocitrate dehydrogenase 1 (IDH1) inhibitor Acute myeloid leukemia Apr 27, 2017
Triciribine phosphate Acute myeloid leukemia Apr 24, 2017
Ac-Leu-Thr-Phe-c[(R)-2-amino-2-methyldec-9-enoic acid-Glu-Tyr-Trp-Ala-Gln-Leu-(S)-2-amino-2-methylhept-6-enoic acid]1-Ala-Ala-Ala-Ala-Ala-D-Ala-NH2 Acute myeloid leukemia Apr 19, 2017
Peptide inhibiting murine double minute 2 (MDM2) and murine double minute X (MDMX) Acute myeloid leukemia Apr 19, 2017
bromodomain and Extra-Terminal (BET) Inhibitor Acute myeloid leukemia Apr 05, 2017
N-[(2S)-5-{[(2S)-2-(4-fluorophenyl)cyclopropyl]amino}-1-(4-methylpiperazin-1-yl)-1-oxopentan-2-yl]-4-(1H-1,2,3-triazol-1-yl)benzamide bis-tosylate salt Acute myeloid leukemia (AML) Feb 07, 2017