Treatment Database

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

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Product Indication Date Designated
Indolino-benzodiazepine compound (sulfonated DGN549-C) conjugated to the humanized anti-CD123 monoclonal antibody (G4723A) Acute myeloid leukemia Oct 10, 2018
2-(3,5-difluoro-3'-methoxybiphenyl-4-ylamino)nicotinic acid Acute myeloid leukemia Aug 16, 2018
apomorphine palmitate Acute Myeloid Leukemia Jun 04, 2018
Indolino-benzodiazepine compound (sulfonated DGN462) conjugated to the humanized anti-CD33 monoclonal antibody (Z4681A) via the sulfo-SPDB linker Acute myeloid leukemia May 02, 2018
Cell-penetrating activating transcription factor 5 mimetic Acute Myeloid Leukemia Apr 30, 2018
7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno [3,2-d]pyrimidin-2-amine semi-fumarate Acute myeloid leukemia Mar 26, 2018
1-{3-fluoro-4-[7-(5-methyl-lH-imidazol-2-yl)- 1-oxo-2,3-dihydro-lH-isoindo 1-4-yl]-phenyl}-3-(3-trifluoromethyl-phenyl)-urea Acute myeloid leukemia (AML) Dec 22, 2017
2-O, 3-O, desulfated heparin Acute myeloid leukemia Dec 21, 2017
THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer Acute myeloid leukemia Oct 24, 2017
6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one monocitrate Acute myeloid leukemia (AML) Oct 03, 2017
1-(2-hydroxyethyl)-8-{[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy) phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide fumarate salt Acute Myeloid Leukemia Sep 28, 2017
ICG136:CD123-CD33cCAR T-cells Acute myeloid leukemia Sep 19, 2017
tetravalent tandem diabody binding both CD3 and CD33 Patients with acute myeloid leukemia (AML) Aug 17, 2017
tamibarotene Acute myeloid leukemia (AML) Aug 16, 2017
Gilteritinib Acute myeloid leukemia (AML) Jul 13, 2017
Glasdegib Acute myeloid leukemia (AML) Jun 28, 2017
chrysoeriol Acute myeloid leukemia Jun 22, 2017
(2S,3S,4E,6S,7R,10R)-7,10-Dihydroxy-3,7-dimethyl-12-oxo-2-[(2E,4E,6R)-6-(pyridin-2-yl)hepta-2,4-dien-2-yl]oxacyclododec-4-en-6-yl 4-methylpiperazine-1-carboxylate Acute myeloid leukemia (AML) Jun 21, 2017
entospletinib Acute myeloid leukemia Jun 15, 2017
Sodium Stibogluconate Acute myeloid leukemia Jun 05, 2017