Close
Close
Treatment Database

The following database contains products that have been granted orphan status, or have been market approval in the EU or the USA.

You can filter the content by clicking on the titles: Product, Indication, Sponsor and Date. Clicking once, will filter the column alphabetically from A – Z and a second click on the same title will filter from Z – A.

Become a Partner.

Product Indication Date Designated
trimetazidine Pulmonary arterial hypertension Aug 07, 2018
N-(tert-butylcarbamoyl)-5-cyano-2-((4'-(difluoromethoxy)-[1,1'-biphenyl]-3-yl)oxy)benzenesulfonamide Pulmonary arterial hypertension Mar 01, 2018
N-(tert-butylcarbamoyl)-5-cyano-2-((4'-(difluoromethoxy)-[1,1'-biphenyl]-3-yl)oxy)benzenesulfonamide Pulmonary arterial hypertension Feb 22, 2018
2-{4-[(9R)-9-Hydroxy-2-(3-hydroxy-3-methylbutyloxy)-9-(trifluoromethyl)-9H-fluoren-4-yl]-1H-pyrazol-1-yl}-2-methylpropanamide monohydrate Pulmonary arterial hypertension Jan 23, 2018
Tacrolimus Pulmonary arterial hypertension Aug 23, 2017
Active calcium sensing receptor antagonist derived from tetrahydropyrazolopyrimidine Pulmonary arterial hypertension Jun 13, 2017
Humanized IgG4 monoclonal antibody that antagonizes endothelin-1 receptor subtype A Pulmonary arterial hypertension (PAH) Jun 06, 2017
(S)-8-{2-amino-6-[1-(5-chloro-biphenyl-2-yl)-(R)-2,2,2-trifluoro-ethoxy]-pyrimidin-4-yl}-2,8-diaza-spiro[4.5]decane-3-carboxylic acid ethyl ester Pulmonary arterial hypertension Apr 20, 2017
nitric oxide Pulmonary arterial hypertension excluding persistent pulmonary hypertension of the newborn Jan 25, 2017
6-(4-(4-(2,3-dichlorophenyl)-piperazin-1-yl)-butoxy)-2H-benzo[b][1,4]oxazin-3(4H)-one hydrochloride Pulmonary arterial hypertension (WHO Group 1) Nov 09, 2016
Partial agonist at the opioid receptor-like 1 receptor with amino acid sequence Ac-Arg-Tyr-Tyr-Arg-Trp-Lys-Lys-Lys-Lys-Lys-Lys-Lys-NH2 Pulmonary arterial hypertension Oct 19, 2016
fixed dose combination formulation of macitentan and tadalafil Pulmonary arterial hypertension Oct 19, 2016
ambrisentan/tadalafil fixed combination Pulmonary arterial hypertension Aug 22, 2016
Ubenimex Pulmonary arterial hypertension Mar 21, 2016
treprostinil sodium solution enclosed within a pre-filled, pre-programmed, single-use, electronically-controlled infusion pump Pulmonary arterial hypertension Dec 29, 2015
(S)-8-{2-Amino-6-[1-(5-chloro-biphenyl-2-yl)-(R)-2,2,2-trifluoro-ethoxy]-pyrimidin-4-yl}-2,8-diaza-spiro[4.5]decane-3-carboxylic acid ethyl ester Pulmonary arterial hypertension (PAH) Oct 06, 2015
tacrolimus Pulmonary arterial hypertension May 04, 2015
bardoxolone Pulmonary arterial hypertension Mar 30, 2015
5-(4-Cyclopropyl-1H-imidazol-l-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide Treatment pulmonary arterial hypertension Jan 15, 2015
(S)-3-((3-(1-((6-((3,4-dimethoxyphenyl)pryazin-2-yl)amino)ethyl)phenyl)carbamoyl)-5-methylpridin-1-ium Pulmonary arterial hypertension Nov 17, 2014