Close
Close
A Groundbreaking Way to Stop Mitochondrial Disease
49 views
1.0
1.0 from 1 vote

For many parents, the decision of when and if they will have a baby is influenced by biological factors outside of their control. Those suffering from inheritable genetic conditions face an especially difficult decision in terms of whether or not to conceive a child. For instance, a mother with mutated mitochondrial DNA (mtDNA) faces an increased possibility that her child will develop an incurable disease with devastating symptoms such as seizures, developmental delay, or organ failure.

University of Newcastle professor Mary Herbert provides parents with a new solution that helps to ensure that the mutations in a mother’s affected mtDNA isn’t passed on to her child. Watch Mary's 2017 TEDMED Talk to see how she is pushing the limits of our understanding of reproduction and looking toward a future where certain mitochondrial diseases can be eliminated from a family for generations to come.

Overview

Mitochondrial disease is a group of disorders caused by dysfunctional mitochondria, the organelles that generate energy for the cell. Mitochondria are found in every cell of the human body except red blood cells, and convert the energy of food molecules into the ATP that powers most cell functions.
Mitochondrial diseases are sometimes (about 15% of the time) caused by mutations in the mitochondrial DNA that affect mitochondrial function. Other causes of mitochondrial disease are mutations in genes of the nuclear DNA, whose gene products are imported into the mitochondria (mitochondrial proteins) as well as acquired mitochondrial conditions. Mitochondrial diseases take on unique characteristics both because of the way the diseases are often inherited and because mitochondria are so critical to cell function. The subclass of these diseases that have neuromuscular disease symptoms are often called a mitochondrial myopathy.

Learn more about:

Clinical Trials

by Abidemi Uruejoma
14 views 6 days ago
by Abidemi Uruejoma
33 views 2 weeks ago
by Abidemi Uruejoma
48 views 3 weeks ago
by Abidemi Uruejoma
47 views 1 month ago
by Abidemi Uruejoma
50 views 1 month ago
by Abidemi Uruejoma
60 views 1 month ago
by Abidemi Uruejoma
59 views 1 month ago
by Abidemi Uruejoma
94 views 1 month ago
by Abidemi Uruejoma
109 views 2 months ago
1.0
1.0 from 1 vote
Free Newsletter
Find a Clinical Trial
Related Videos
by Scott Harwood
189 views